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Medicine

The COVID Conversation

Sandro Galea

Policymakers and the media have reacted hastily to COVID-19 research, and not always for the best. Scientific researchers now have new responsibilities to contextualize their findings for the public.

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Medicine

Inequality and Instability in the Time of COVID-19

Walter Scheidel

COVID-19 has widened fault lines between the advantaged and disadvantaged. Yet while many past crises leveled inequality, stabilizers in the modern economy may prevent social and policy reform.

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Medicine

Digital Contact Tracing in South Korea

Jae Chun Choe

South Korea has impressively managed its COVID-19 crisis without lockdowns, roadblocks, or immigration controls. This is only possible given rapid and effective testing and contact tracing systems.

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Mathematics

Exponential Growth

Sheldon Lee Glashow

Exponential growth features frequently in epidemiological projections. Because of carelessness or ignorance, its implications can be easily, and sometimes grievously, underestimated.

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Medicine

The Physiology and Biophysics of Respiratory Therapy

J. Scott Turner

Though carrying a suite of risks, high-frequency ventilation may be a safer and more effective treatment than the positive-pressure ventilation that is most commonly used in severe COVID-19 cases.

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Medicine

Cytokine Storms

Tyler Hampton

Cytokine storms may be fatal and can occur as a result of many different triggers. A growing body of literature suggests a connection between SARS-CoV-2 infection and the induction of cytokine storms.

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Medicine

The Virus

Marc Henry

The coronaviruses: what they are and what phylogenetic analyses reveal about the relationships between SARS-CoV-2 and bat and pangolin coronaviruses.

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Medicine

Antimalarial Drugs as COVID-19 Therapy

J. Scott Turner

Chloroquine and hydroxychloroquine—a history of their uses, and how they work in the very different cases of the malaria parasite and viral infections, such as SARS-CoV-2.

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Economics

An End to Globalization

Michael O’Sullivan

The coronavirus crisis marks a transition to a new order in politics, economics, finance, and geopolitics. A contested century is in prospect, driven by a battle of emerging philosophies.